Piccirillo Sinus Study in Top 20 Read

Nearly every major news feed across the US and even international sources in India, Canada, Australia, and others are giving headline attention to a new study released by the Journal of the American Medical Association (JAMA). The study authors, Jane M. Garbutt, Christina Banister, Edward Spitznagel and Jay F. Piccirillo, are all from Washington University School of Medicine. The study sought to verify support for antibiotic treatment of acute rhinosinusitis and determine the incremental advantage of antibiotics over symptomatic treatment using over-the-counter remedies. The clinical trial included 166 local adult patients that were randomized to receive amoxicillin or a placebo. All patients received symptomatic treatments for pain, fever, cough or nasal congestion as needed. Study outcomes were assessed by telephone interview at 3, 7, 10 and 28 days following the start of treatment, using the Sinonasal Outcome Test-16 (SNOT-16). The study found that a ten-day course of amoxicillin did not significantly reduce symptoms at day 3 of treatment compared to placebo.

The official JAMA news release can be found here and the JAMA author interview with Dr. Piccirillo, here.

Check out some of the many major news follow-ups:

In addition, the article was recently named as one of the top 20 most read articles of 2012 in the specialty of otolaryngology. Congratulations to Dr. Piccirillo and his team of researchers!