Brian Nussenbaum, MD, FACS

Christy J. & Richard S. Hawes, III Professor
Vice Chair for Clinical Affairs
Division Chief, Head and Neck Surgical Oncology
Patient Safety Officer
Co-Director, Fellowship in Head and Neck Oncology and Reconstruction

WU Physicians Bio

Dr. Nussenbaum's clinical interests include: head and neck benign and malignant tumors, squamous cell carcinoma, melanoma; skull base surgery and facial nerve problems; parotid and other salivary gland problems and tumors; thyroid and parathyroid diseases; glomus tumors; throat cancer, throat surgery, conservation surgery of the larynx, free flap reconstruction, sialendoscopy

Patients Seen At:

Mailing Address:

Center for Advanced Medicine
Ear, Nose and Throat Center
4921 Parkview Place, Suite A, Floor 11
St. Louis, MO 63110
(314) 362-7509
Fax: (314) 747-5593

Washington University School of Medicine
Department of Otolaryngology-Head and Neck Surgery
660 So. Euclid Avenue, Campus Box 8115
St. Louis, MO 63110


  • B.A.: Mathematics, State University of New York , Binghamton, New York, 1990
  • Medical Degree: New York University School of Medicine, New York, New York, 1994
  • Elective Training: Otorhinolaryngic and Endocrine Pathology, Armed Forces Institute of Pathology, Washington, D.C., 1998
  • Residency: Otorhinolaryngology, University of Texas Southwestern, Dallas, Texas, 2000
  • Fellowship : Head and Neck Oncology, Microvascular Reconstructive Surgery, University of Michigan, Ann Arbor, Michigan, 2002

Licensure and Board Certification

  • Otolaryngology--Certified


  • Listed in Best Doctors in America, 2007-2012 (Best Doctors, Inc)
  • Elected for America’s Top Doctors, Castle Connolly Medical Ltd, 2011, 2012
  • Teacher of the Year, Department of Otolaryngology, Washington University, 2003, 2006, 2008, 2011, 2012
  • Honorable Mention Award for Basic Science Research The Triological Society, 2004
  • Alpha Omega Alpha, New York University School of Medicine, 1994
  • Phi Betta Kappa, State University of New York at Binghamton, 1990

Selected Publications

  1. Desai SC, Sand JP, Sharon JD, Branham G, Nussenbaum B. Scalp Reconstruction: An algorithmic Approach and Systematic Review. JAMA Facial Plast Surg 2014; Nov 6 [Epub ahead of print]

  2. Blank SJ, Grindler DJ, Zerega J, Blinder M, Nussenbaum B. Systemic effects of subcutaneous heparin use in otolaryngology patients. Otolaryngol Head Neck Surg 2014; Sep 25 [Epub ahead of print]

  3. Sand JP, Haughey BH, Nussenbaum B. Asymptomatic p16-positive oropharyngeal squamous cell carcinoma: an emerging trend. JAMA Otolaryngol Head Neck Surg 2014; Sep 11 {Epub ahead of print]

  4. Graboyes EM, Bradley JP, Kallogjeri D, Cavallone LF, Nussenbaum B. Prognosis and patterns of failure for the extubation of patients who remain intubated after head and neck surgery. Ann Otol Rhinol Laryngol 2014; Sep 9 [Epub ahead of print]

  5. Graboyes EM, Yang Z, Kallogjeri D, Diaz JA, Nussenbaum B. Patients undergoing total laryngectomy: an at-risk population for 30-day unplanned readmission. JAMA Otolaryngol Head Neck Surg 2014; Aug 21 [Epub ahead of print]

  6. Spencer CR, Gay HA, Haughey BH, Nussenbaum B, Adkins DR, Wildes TM, DeWees TA, Lewis JS Jr, Thorstad WL. Eliminating radiotherapy to the contralateral retropharyngeal and high level II lymph nodes in head and neck squamous cell carcinoma is safe and improves quality of life. Cancer 2014; Aug 20 [Epub ahead of print]

  7. Sinha P, Hackman T, Nussenbaum B, Wu N, Lewis JS, Haughey BH. Transoral laser microsurgery for oral squamous cell carcinoma: oncologic outcomes and prognostic factors. Head Neck. 2014; 36: 340-351.

  8. Sand JP, Kokorina NA, Zaharkin SO, Lewis JS Jr, Nussenbaum B. BMP-2 expression correlates with local failure in head and neck squamous cell carcinoma. Otolaryngol Head Neck Surg 2014; 150: 245-250.

  9. Liou TN, Nussenbaum B. Wrong site surgery in otolaryngology-head and neck surgery. Laryngoscope 2014; 124: 104-109.

  10. Becker N, Chernock RD, Nussenbaum B, Lewis JS. Prognostic significance of beta-human chorionic gonadotropin and PAX8 expression in anaplastic thyroid carcinoma. Thyroid. 2014; 24: 319-326.

  11. Sinha P, Thorstad WL, Nussenbaum B, Haughey BH, Adkins DR, Kallogjeri D, Lewis JS Jr. Distant metastasis in p16 positive oropharyngeal squamous cell carcinoma: a critical analysis of patterns and outcomes. Oral Oncol 2014; 50: 45-51.

  12. Sinha P, Mehrad M, Chernock RD, Lewis JS Jr, El-Mofty SK, Wu N, Nussenbaum B, Haughey BH. Histologic and systemic prognosticators for local control and survival in margin negative transoral laser microsurgery-treated oral cavity squamous cell carcinoma. Head Neck 2013; Nov 8 [Epub ahead of print]

Book Chapters

  1. Nussenbaum B. Reconstruction of the Mandible. Textbook chapter (#97) in Otolaryngology Head & Neck Surgery, 5th edition, edited by Flint PW, Haughey BH, Lund VJ, Niparko JK, Richardson MA, Robbins KT, Thomas JR, 2010; updated as chapter #94 in 2014.

  2. Rigby MH, Nussenbaum B, Hinni ML, Lott DG. Transoral surgery for chemoradiation failures. Textbook chapter (#13) in Contemporary Transoral Surgery for Primary Head and Neck Cancer, edited by Hinni ML, and Lott DG, 2014.

  3. DG, Crujido L, Nussenbaum B. Functional outcomes of transoral surgery. Textbook chapter (#15) in Contemporary Transoral Surgery for Primary Head and Neck Cancer, edited by Hinni ML, and Lott DG, 2014.