Tejbeer Kaur, PhD
Instructor, Otolaryngology - Head and Neck Surgery
My research goal is to establish a deep understanding of the nature and function of neuron-immune interactions along the auditory pathway during development and disease and understand the contributions of immune system towards neurodegeneration, protection and regeneration in deafened ears. I am currently investigating the influence of macrophages (innate-immune cells) on neuronal, axonal and synaptic pathology in animal models of human sensorineural hearing loss. In parallel, I am studying to understand the role of cochlear resident macrophages during development, maturation and homeostasis.
Washington University School of Medicine
660 S. Euclid Ave.
Campus Box 8115
St. Louis, MO 63110
- BS, Pharmacy, University of New Delhi, India (2005)
- MS, Pharmacology, University of New Delhi, India (2008)
- PhD, Pharmacology and Neuroscience, SOuthern Illinois University, Carbondale, IL (2012)
- Postdoctoral Fellowship in Auditory Neurobiology, Washington University in St. Louis, St. Louis, MO (2016)
- 2013 - Scholarship, Biology of Inner Ear, Marine Biological Laboratory, Woods Hole, MA
- 2012 - Third prize, 22nd Annual Trainee Research Symposium, Southern Illinois University, Carbondale, IL
- 2012 - Outstanding Scholar, Pharmacology, Southern Illinois University, Carbondale, IL
- 2011 - Travel Award, Association for Research in Otolaryngology, 34th ARO Midwinter Meeting
- 2010 - First prize, 20th Annual Trainee Research Symposium, Southern Illinois University, Carbondale, IL
- 2006 - Merit Scholar, MS in Pharmacology, University of Delhi, India
- 2004 - Merit Scholar, BS in Pharmacy, University of Delhi, India
- Ohlemiller KK , Kaur T, Warchol ME , Withnell R (2018). The Endocochlear Potential as an Indicator of Reticular Lamina Integrity after Noise Exposure in Mice. Hearing Research.
- Kaur T, Ohlemiller KK, Warchol ME (2018). Genetic disruption of fractalkine signaling leads to enhanced loss of cochlear afferents following ototoxic or acoustic injury. Journal of Comparative Neurology.
- Vikrant Borse, Tejbeer Kaur, Kelly Sheehan, Sandeep Sheth, Debashree Mukherjea, Raheem Al Aameri, Srinivasan Tupal, Michelle Lowy, Sumana Ghosh, Asmita Dhukhwa, Puspanjali Bhatta, and Leonard P Rybak, and Vickram Ramkumar (2017). Epigallocatechin-3-Gallate (EGCG), a Prototypic Chemo-Preventative Agent for Protection against Cisplatin-Based Ototoxicity. Cell Death and Disease.
- Tejbeer Kaur, Vikrant Borse, Sandeep Sheth, Kelly Sheehan, Sumana Ghosh, Srinivasan Tupal, Sarvesh Jajoo, Debashree Mukherjea, Leonard Rybak, and Vickram Ramkumar (2016). Adenosine A1 Receptor Protects Against Cisplatin Ototoxicity by Suppressing the NOX3/STAT1 Inflammatory Pathway in the Cochlea. The Journal of Neuroscience.
- Kaur T, Zamani D, Tong L, Rubel EW, Ohlemiller KK, Hirose K, Warchol ME (2015). Fractalkine signaling regulates macrophage recruitment into the cochlea and promotes the survival of spiral ganglion neurons after selective hair cell lesion. The Journal of Neuroscience.
- Kaur T, Hirose K, Rubel EW and Warchol ME (2015). Macrophage recruitment and epithelial repair following hair cell injury in the mouse utricle. Frontiers in Cellular Neuroscience.
- Tong L, Strong M, Kaur T, Juiz J, Oesterle E, Hume C, Warchol M, Palmiter R, and Rubel E (2015). Selective deletion of cochlear hair cells causes rapid age-dependent changes in spiral ganglion and cochlear nucleus neurons. The Journal of Neuroscience.
- Jajoo S, Mukherjea D, Kaur T, Sheehan KE, Sheth S, Borse V, Rybak LP, Ramkumar V (2013). Essential role of NADPH oxidase-dependent reactive oxygen species generation in regulating microRNA-21 expression and function in prostate cancer. Antioxid Redox Signal.
- Sandeep Sheth, Sarvesh Jajoo, Tejbeer Kaur, Debashree Mukherjea, Kelly Sheehan, Leonard Rybak and Vickram Ramkumar (2012). Resveratrol Reduces Prostate Cancer Growth and Metastasis by Inhibiting MicroRNA-21 Expression. PLoS One.
- Tejbeer Kaur, Debashree Mukherjea, Kelly Sheehan, Sarvesh Jajoo, Leonard P. Rybak, and Vickram Ramkumar (2011). Short Interfering RNA Against STAT1 Attenuates Cisplatin Induced Ototoxicity in the Rat by Suppressing Inflammation. Cell Death and Disease (Nature Publishing Group).