The overall goal of our research is to study the role of the vestibulo-cerebellum in motor control, balance and spatial navigation. The vestibulo-cerebellum is a region of the cerebellar cortex that comprises the floccular lobe and the posterior vermis. Currently, our lab is testing the hypothesis that the floccular lobe computes a forward model (predictive model) of the eye movement from vestibular and efferent copy information, and that the posterior vermis computes an estimate of our heading (translation) and orientation in space from semicircular canals and otolith information. Our experimental techniques include single unit recordings, pharmacology, behavioral neuroscience, mouse neurogenetics, histochemistry and computational modeling.
Health problems associated with motor control and balance are the most common neurological disorders affecting the world population today. Our research is aimed to understanding motor control and balance in the normal and diseased brain, with the ultimate goal of paving the way towards finding cures and therapies for rehabilitation.