Publication List for Alec Salt
Recent Publications : 2008
Plontke SK, Biegner T, Kammerer B, Delabar U, Salt AN. Dexamethasone concentration gradients along scala tympani after application to the round window membrane. Otology & Neurotology (in press).Harris, J.P., Salt, A.N. Meniere's Disease. In: Dallos P (Ed), Handbook of the Senses (in press)
Salt AN, Hartsock JJ, Gill RM Functional Changes Associated with "One-Shot" Intracochlear Injections through the Round Window Membrane. 31st Midwinter Research Meeting of the ARO, 2008.
Mikulec AA, Plontke SK, Hartsock JJ, Salt AN Drugs Enter the Perilymph of Guinea Pigs through the Bony Otic Capsule. 31st Midwinter Research Meeting of the ARO, 2008.
Siedow, N, Hering-Bertram M, Gill RM, Salt AN, Plontke SK. Development of a three-dimensional model for calculation of substance distribution in the inner ear after round window application based on a realistic geometry of the guinea pig inner ear. 31st Midwinter Research Meeting of the ARO, 2008.
Publications : 2007
Salt, A.N., Sirjani, D.B., Hartsock, J.J., Gill, R.M., Plontke, S.K. Marker Retention in the Cochlea Following Injections through the Round Window Membrane. Hear Res. 2007;232:78-86.Plontke, S.K., Siedow, N, Wegener, R., Zenner, H.-P., Salt, A.N. Cochlear pharmacokinetics with local inner ear drug delivery using a 3D finite element computer model Audiology & Neurootology 12:37-48, 2007 (17119332).
Plontke SK, Mynatt R, Gill RM., Salt AN. Concentration gradient along scala tympani following the local application of gentamicin to the round window membrane. Laryngoscope. 117:1191-1198, 2007.
Salt, A.N. The endolymphatic sinus is a possible detector of endolymph volume status. A response to Wit,HP, Hofman, R. "Does the endolymph sinus function as a one-way valve?" Hear. Res 224:117-118, 2007.
Harding GW, Bohne BA, Lee SC, Salt AN. Effect of infrasound on cochlear damage from exposure to a 4kHz octave band of noise. Hear Res. 225:128-138 2007 (17300889).
Salt A.N. Endolymph physiology in Meniere's disease. Invited speaker: Workshop on Meniere's disease. 30th Midwinter Research Meeting of the ARO, 2007.
Salt, A.N., Holden, T.A., Gill, R.M., Plontke, S.K. Modeling drug dispersion in the inner ear fluids: The importance of accurate 3D anatomical studies. Invited speaker: Workshop on 3D imaging, modeling, reconstruction and analysis of the temporal bone and brain. 30th Midwinter Research Meeting of the ARO, 2007.
Salt, A.N., Hartsock, J.J., Sirjani, D.B., Plontke, S.K. Perilymph pharmacokinetics following one-shot injections into the basal cochlear turn of guinea pigs. 30th Midwinter Research Meeting of the ARO, 2007.
Plontke, S.K., Beigner, T. Kammerer, B., Salt, A.N. Dexamethasone concentration gradient along scala tympani of the guinea pig cochlea after round window drug administration. 30th Midwinter Research Meeting of the ARO, 2007.
Mikulec, A.A., Salt, A.N. Factors influencing round window membrane permeability in guinea pigs. 30th Midwinter Research Meeting of the ARO, 2007.
Salt, AN Cochlear fluids homeostasis and its relevance to drug delivery to the inner ear. Equilibrium Research. 2007: 66, 206 (abstract).
Publications : 2006
Mynatt, R., Hale, S.A., Gill, R.M., Plontke, S.K.R., Salt, A.N. Demonstration of a longitudinal concentration gradient along scala tympani by sequential sampling of perilymph from the cochlear apex. J Assoc Res Otolaryngol. 7:182-193, 2006. (16718612)Hahn, H., Kemmerer, B., DiMauro, A., Salt, A.N., Plontke, S. Cochlear microdialysis for quantification of dexamethasone and fluorescein entry into scala tympani during round window administration. Hearing Research 212:236-244, 2006. (16442251) Full paper available Elsevier:Hearing Research
Salt, A.N., Hale S.A., Plontke, S.K.R. Perilymph Sampling from the Cochlear Apex: A Reliable Method to Obtain Higher Purity Perilymph Samples from Scala Tympani. Journal of Neuroscience Methods 153: 121-129, 2006 (16310856) Full paper available Elsevier:Journal of Neuroscience Methods
Plontke, S.K., Salt, A.N. Simulation of Application Strategies for Local Drug Delivery to the Inner Ear. ORL 68:382-388, 2006. (17065834)
Mynatt, R., Plontke, S., Hale S., Gill, R. Salt, A.N. Sequential apical sampling from the cochlea as a method to quantify longitudinal drug gradients: Validation with an ionic marker. 29th Midwinter Research Meeting of the ARO, Baltimore, February 2006.
Salt, A.N., Hale, S. Transducer operating point changes during endolymph volume manipulations detected by low-frequency biased f2-f1 acoustic emissions. 29th Midwinter Research Meeting of the ARO, Baltimore, February 2006.
Salt, A.N., Gill, R., Voie, A., Saxon, G. 3D Representation of the guinea pig inner ear and the implications for modeling drug movements in the fluids. 29th Midwinter Research Meeting of the ARO, Baltimore, February 2006.
Plontke S.,Mynatt, R. Hale, S., Salt, A.N. Gentamicin concentration gradient along scala tympani of the guinea pig cochlea after round window drug administration. 29th Midwinter Research Meeting of the ARO, Baltimore, February 2006.
Salt, A.N. Entering the cochlea : the final frontier. University College London symposium on directions in hearing research. May 2006.
Salt A.N. Fluid distribution - Inner ear drug delivery. Hearing Preservation Workshop V, Research Triangle Park, NC., October 2006.
Publications : 2005
Salt, A.N. Phamacokinetics of drug entry into cochlear fluids. In: Aminoglycoside Ototoxicity: Mechanisms and Strategies in Prevention. Ed. Steyger. P. The Volta Review 105 (3), 277-298, 2005, Washington DC. ISSN 0042-8639 Full paper available Alexander Graham Bell Association: The Volta ReviewBobbin, R.P. and Salt, A.N. ATP-g-S Shifts the Operating Point of Outer Hair Cell Transduction Toward Scala Tympani. Hear. Res. 205, 35-43, 2005. Full paper available Elsevier:Hearing Research
Salt, A.N. and Plontke, S.K.R. Local Inner ear drug delivery and pharmacokinetics. In: Hearing Research and Drug Discovery : Drug Discovery Today. 10:1299-1306, 2005. Full paper available Drug Discovery Today
Plontke, S. and Salt, A. Pharmacokinetic Considerations of Local Drug Delivery to the Inner Ear by Round Window Application. Proceedings of the 5th International Symposium on Meniere’s Disease and Inner Ear Homeostasis Disorders, 2005; David J. Lim, editor; House Ear Institute, Los Angeles, CA, publishers. ISBN 0-9776204-0-9. Full paper available The House Institute
Salt, A.N. Low Frequency Pressure Changes may Participate in Endolymph Volume Regulation. Proceedings of the 5th International Symposium on Meniere’s Disease and Inner Ear Homeostasis Disorders, 2005; David J. Lim, editor; House Ear Institute, Los Angeles, CA, publishers. ISBN 0-9776204-0-9. Full paper available The House Institute
Salt, A.N., Henson, H.E., Gill, R.M., Sirjani, D.B. Even-Order Distortion as an Indicator of Endolymphatic Hydrops. Proceedings of the 5th International Symposium on Meniere’s Disease and Inner Ear Homeostasis Disorders, 2005; David J. Lim, editor; House Ear Institute, Los Angeles, CA, publishers. ISBN 0-9776204-0-9. Full paper available The House Institute
Kakigi, A., Salt, A.N., Takeda T. Effect of artificial endolymph injection into the cochlear duct on perilymph potassium. Proceedings of the 5th International Symposium on Meniere’s Disease and Inner Ear Homeostasis Disorders, 2005; David J. Lim, editor; House Ear Institute, Los Angeles, CA, publishers. ISBN 0-9776204-0-9.
Garnham, C., Reetz, G., Jolly, C., Miller, J., Salt, A., Beal, F. Drug delivery to the cochlea after implantation: Consideration of the risk factors. Cochlear Implants International 6 (SUPPL. 1), pp. 12-14, 2005.
Salt, A.N., Mynatt, R.., Hale, S., Plontke, S.K. Scala tympani perilymph sampling from the cochlear apex. Inner Ear Biology Meeting, Tuebingen, Sept 2005 Abstract available
Salt, A.N. Mechanisms of endolymph homeostasis in the inner ear. COSM (Otologic Society) Boca Raton, FL, May 2005. Abstract available
Salt, A. and Hale, S. Longitudinal Distribution of Drugs in Perilymph Assessed by Cochlear Action Potentials. 28th Midwinter Research Meeting of the ARO, New Orleans, February 2005. Abstract available
Salt, A. and Gill, R. Dependence of Distortion on Cochlear Transducer Characteristics. 28th Midwinter Research Meeting of the ARO, New Orleans, February 2005. Abstract available
Salt, A and Henson, H. Influence of Low Frequency Biasing on Distortion Generation by the Cochlea. 28th Midwinter Research Meeting of the ARO, New Orleans, February 2005.
Plontke, S., Siedow, N., Salt, A.N., Zenner, H-P., Wegener, R. Further Development of the Three-dimensional Model of Substance Distribution in the Cochlea after Round Window Application. 28th Midwinter Research Meeting of the ARO, New Orleans, February 2005.
Hahn, H., Kammerer, A., DiMauro, A., Zenner, H.-P., Salt, A.N., Plontke, S. The use of Microdialysis for Quantification of Dexamethasone and Flourescein Entry into Scala Tympani during Round Window Application. 28th Midwinter Research Meeting of the ARO, New Orleans, February 2005.
Publications : 2004
Salt, A.N. Acute endolymphatic hydrops generated by exposure of the ear to non-traumatic low frequency tone. JARO 5, 203-214, 2004. Abstract available Full paper available Springer:JAROSalt, A.N and Rask-Andersen, H. Responses of the endolymphatic sac to perilymphatic manipulations: Evidence for the presence of a one-way valve. Hear. Res 191, 90-100, 2004. Abstract available Full paper available Elsevier:Hearing Research
Sirjani, D.B., Salt, A.N., Gill, R.M., Hale, S.A. The influence of transducer operating point on distortion generation in the cochlea. JASA 115 (3), 1219-1229, 2004. Abstract available Full paper available Journal of the Acoustical Society
Plontke, S, Siedow, N., Hahn, H., Wegener, R., Zenner, H.P., Salt, A.N. 1D-and 3D- computer simulation for planning and interpretation of pharmacokinetic studies in the inner ear after round window drug delivery. ALTEX. 21 Suppl 3:77-85, 2004 (article in German). Abstract available Full paper available Elsevier
Salt, A.N., Rask-Andersen, H. Responses of the endolymphatic sac to perilymphatic pressure manipulations suggest the presence of a one-way valve. 27th Midwinter Research Meeting of the ARO, 2004. Abstract available
Salt, A.N., Hale, S.A. Evaluation of a novel method for sampling scala tympani perilymph by collecting fluid from the cochlear apex. 27th Midwinter Research Meeting of the ARO, 2004. Abstract available
Sirjani, D.B., Salt, A.N., Gill, R.M., Hale, S.A. Interpretation of distortion changes during endolymphatic manipulations by an analysis of transducer operating point. 27th Midwinter Research Meeting of the ARO, 2004. Abstract available
Rodger, C.S., Salt, A.N. Transducer operating point shifts account for post-onset distortion changes with low frequency tones. 27th Midwinter Research Meeting of the ARO, 2004. Abstract available
Papers 2003 and earlier - Reviewed Journal Articles
Plontke, S.K.R. and Salt, A.N. Quantitative interpretation of corticosteroid pharmacokinetics in inner ear fluids using computer simulations. Hearing Research 182, 34-42, 2003. Abstract available Full paper available Elsevier:Hearing Research
Salt, A.N., Kellner, C., Hale, S. Contamination of perilymph sampled from the basal cochlea turn with cerebrospinal fluid. Hearing Research 182, 24-33, 2003 Abstract available Full paper available Elsevier:Hearing Research
Pettit, K., Henson, M.M., Henson, O.W.jr, Gewalt, S.L., Salt, A.N. Quantitative anatomy of the guinea pig endolymphatic sac. Hearing Research 174: 1-8, 2002. Abstract available Full paper available Elsevier:Hearing Research
Plontke, S.K.R., Wood, A.W., Salt, A.N. Analysis of gentamicin kinetics in fluids of the inner ear with round window administration. Otology and Neurotology 23: 967-974, 2002. Abstract available Full paper available Otology and Neurotology
Ghiz, A.F., Salt, A.N., DeMott, J.E., Henson, M.M., Henson, O.W., jr., Gewalt, S.L. Quantitative anatomy of the round window and cochlear aqueduct in guinea pigs. Hearing Research. 162: 105-112, 2001. Abstract available Full paper available Elsevier:Hearing Research
Salt, A.N. and Ma, Y. Quantification of solute entry into cochlear perilymph through the round window membrane. Hearing Research 154, 88-97, 2001. Abstract available Full paper available Elsevier:Hearing Research
Salt, A.N., DeMott, J.E. Ionic and potential changes of the endolymphatic sac induced by endolymph volume changes. Hearing Research 149, 46-54, 2000 Abstract available Full paper available Elsevier:Hearing Research
Rask-Andersen, H., Salt, A.N., DeMott, J.E. and Bagger-Sjoback, D. Morphological changes of the endolymphatic sac induced by microinjection of artificial endolymph into the cochlea. Hearing Research 138: 81-90, 1999. Abstract available Full paper available Elsevier:Hearing Research
Salt, A.N. and DeMott, J.E. Longitudinal endolymph movements and endocochlear potential changes induced by stimulation at infrasonic frequencies. Journal of the Acoustical Society of America 106: 847-856, 1999. Abstract available
Thorne, M., Salt, A.N., DeMott, J.E., Henson, M.M., Henson, O.W. jr. And Gewalt, S.L. Cochlear fluid space dimensions for six species derived from reconstructions of 3-D magnetic resonance images. Laryngoscope 109: 1661-1668, 1999. Abstract available
Salt, A.N. and DeMott, J.E. Longitudinal endolymph movements induced by perilymphatic injections. Hearing Research 123: 137-147, 1998 Abstract available
Brunschwig, A.S. and Salt, A.N. Fixation-induced shrinkage of Reissner's membrane and its potential influence in the assessment of endolymph volume. Hearing Research 114: 62-68, 1997. Abstract available
Gill, S.S and Salt, A.N. Quantitative differences in endolymphatic calcium and endocochlear potential between pigmented and albino guinea pigs. Hearing Research 113: 191-197, 1997. Abstract available
Salt, A.N. and DeMott, J.E. Longitudinal endolymph flow associated with acute volume increase in the cochlea. Hearing Research 107: 29-40, 1997 Abstract available
Salt, A.N., Henson, M.M., Gewalt, S.L., Keating, A.W., DeMott, J.E.and Henson, O.W.: Detection and quantification of endolymphatic hydrops in the guinea pig cochlea by magnetic resonance microscopy. Hearing Research 88: 79-86, 1995. Abstract available
Salt, A.N. and DeMott, J.E.: Endolymph volume changes during osmotic dehydration measured by two marker techniques. Hearing Research 90: 12-23, 1995. Abstract available
Salt, A.N., DeMott, J.E. and Kimura, R.S.: Comparison of histologically-measured endolymph cross-sectional area with that measured in vivo using an ionic volume marker. Annals of Otol-Rhinol-Laryngol. 104, 886-894, 1995. Abstract available
Salt, A.N. and DeMott, J.D.: Time course of endolymph volume increase in experimental hydrops measured in vivo with an ionic volume marker. Hearing Res. 74:165-172, 1994.
Salt, A.N. and DeMott, J.D.: Endolymph calcium increases with time after surgical induction of hydrops in guinea-pigs. Hearing Res. 74:115-121, 1994.
Ito, Z., Kusakari, J., Salt, A.N.: Solute movement across the round window membrane in comparison with that across the blood labyrinth barrier. Jap. J. Otolaryngol. 95:1959-1967, 1993.
Inamura, N. and Salt, A.N.: Permeability changes of the blood-labyrinth barrier measured in vivo during experimental treatments. Hearing Res. 61:12-18, 1992.
Salt, A.N. and Ohyama, K.: Accumulation of potassium in scala vestibuli perilymph of the mammalian cochlea. Ann ORL 102:64-78, 1993.
Salt, A.N. and DeMott, J.: Tetramethylammonium for in vivo marking of the cross-sectional area of the scala media in the guinea-pig cochlea. Archives Oto-Rhino-Laryngology 249:157-163, 1992.
Salt, A.N., Ohyama, K and Thalmann, R.: Radial communication between the perilymphatic scalae of the cochlea. II. Estimation by bolus injection of tracer into the sealed cochlea. Hearing Res. 56:37-43, 1991
Salt, A.N., Ohyama, K and Thalmann, R.: Radial communication between the perilymphatic scalae of the cochlea. I. Estimation by tracer perfusion. Hearing Res. 56:29-36, 1991
Salt, A.N., Inamura, N., Thalmann, R. and Vora, A.R.: Evaluation of procedures to reduce fluid flow in the fistulized guinea-pig cochlea. Acta Otolaryngol. 111:899-907, 1991
Salt, A.N. and Vora, A.R.: Calibration of ion selective microelectrodes for use with high levels of interfering ions. J. Neuroscience Methods 38:233-237, 1991
Salt, A.N. and Garcia, P.: Cochlear action potential tuning curves recorded with a derived response technique. J. Acoust. Soc. Amer. 88:1392-1402, 1990.
Salt, A.N. and Vora, A.R.: Cochlear threshold assessment using tone-derived action potentials. Audiology 29:135-145, 1990.
Salt, A.N., Inamura, N., Thalmann, R. and Vora, A.: Calcium gradients in inner ear endolymph. Am. J. Otol. 10:371-375, 1989.
Hara, A., Salt, A.N. and Thalmann, R.: Perilymph composition in scala tympani of the cochlea: Influence of cerebrospinal fluid. Hearing Res. 42:265-272, 1989.
Ohyama, K., Salt, A.N. and Thalmann, R.: Volume flow rate of perilymph in the guinea-pig cochlea. Hearing Res. 35:119-130, 1988.
Salt, A.N. and Thalmann, R.: Interpretation of endolymph flow results. Hearing Res. 33:279-281, 1988.
Salt, A.N. and Thalmann, R.: New concepts regarding the volume flow of endolymph and perilymph. Adv. Oto-Rhino-Laryngol. 37:11-17, 1987.
Salt, A.N., Melichar, I. and Thalmann, R.: Mechanisms of endocochlear potential generation by stria vascularis. Laryngoscope, 97:984-991, 1987.
Salt, A.N., Thalmann, R., Marcus, D.C. and Bohne, B.A.: Direct measurement of longitudinal endolymph flow rate in the guinea pig cochlea. Hearing Res. 23:141-151, 1986.
Salt, A.N. and Thornton, A.R.D.: The effects of stimulus rise-time and polarity on the brainstem responses. Scand. Audiol. 13:119-128, 1984.
Blunn, R.W., Salt, A.N. and Thornton, A.R.D.: Construction of a simple stimulus polarity indicator. Electroenceph. and Clin. Neurophysiol. 56:689-690, 1983.
Konishi, T. and Salt, A.N.: Electrochemical profile for potassium ions across the cochlear hair cell membranes of normal and noise-exposed guinea pigs. Hearing Res. 11:219-233, 1983.
Konishi, T., Salt, A.N. and Hamrick, P.E.: Effects of exposure to noise on the permeability to potassium of the endolymph/perilymph barrier. Acta Otolaryngol. 94:395-402, 1982.
Cook, R.O., Konishi, T., Salt, A.N., Hamm, C.W., Lebetkin, E.H. and Koo, J.: Brainstem evoked responses in guinea pig exposed to high noise levels in utero. Develop. Psychology, 15:95-104, 1982.
Salt, A.N. and Konishi, T.: Functional importance of sodium and potassium in the guinea pig cochlea studied with amiloride and tetraethylammonium. Jap. J. Physiol. 32:219-230, 1982.
Konishi, T., Salt, A.N. and Hamrick, P.E.: Effects of hypothermia on ionic movement in the guinea pig cochlea. Hearing Res. 4:265-278, 1981.
Salt, A.N., Konishi, T., Cook, R.O. and Akay, A.: Comparison between the effects of continuous and impact noise on guinea pig cochlear potentials. J. Acoust. Soc. Amer. 69:1746-1752, 1981.
Konishi, T. and Salt, A.N.: Permeability to potassium of the endolymph-perilymph barrier and its possible relation to hair cell function. Exp. Brain Res. 40:457-463, 1980.
Salt, A.N. and Konishi, T.: Effects of noise on cochlear potentials and endolymph potassium concentration recorded with potassium-selective electrodes. Hearing Res. 1:343-363, 1979.
Konishi, T., Salt, A.N. and Hamrick, P.E.: Effects of exposure to noise on ion movement in the guinea pig cochlea. Hearing Res. 1:325-342, 1979.
Salt, A.N. and Stopp, P.E.: The effect of cerebrospinal fluid pressure on perilymphatic flow in the opened cochlea. Acta Otolaryngol. 88:198-202, 1979.
Salt, A.N. and Stopp, P.E.: The effect of raising scala tympani potassium concentration on the tone-induced cochlear responses in the guinea pig. Exp. Brain Res. 36:87-98, 1979.
Chapters / Invited Papers
Salt, A.N. Regulation of endolymphatic fluid volume. In: The vestibular labyrinth in health and disease. Eds. Highstein, S. and Goebel, J. Annals NY Academy of Science. 942: 306-312, 2001. Full paper available
Salt, A.N. Simulation of methods for drug delivery to the cochlear fluids. Adv Otorhinolaryngol. 2002, 59:140-8.
Salt, A.N. Dynamics of the inner ear fluids. In: Jahn A.F. and Santos-Sacchi, J., Physiology of the Ear, Second Edition. Singular press, pp 333-356, 2001.
Rask-Anderson, H., Kinnefors, A., Salt, A., DeMott, J.E., Illing, R.B. Homeostatic mechanisms of the inner ear fluids. In: Meniere's Disease (Proceeding of th 4th International symposium on Meniere's disease, Paris, 1999) Eds Sterkers, O., Ferrary, E., Dauman, R., Sauvage, J.P., Tran Ba uy P. Kugler publications, The Hague, The Netherlands, pp 59-73, 2000
Salt, A.N. and DeMott, J.E. The role of endolymph flow in homeostasis. In: Meniere's Disease (Proceeding of the 4th International symposium on Meniere's disease, Paris, 1999). Eds. Sterkers, O., Ferrary, E., Dauman, R., Sauvage, J.p., Tran Ba Huy P. Kulger publications, The Hague, The Netherlands, pp 41-45, 2000.
Salt, A.N. Fluid homeostasis in the inner ear. In: Meniere's Disease, Ed. Harris, J.P., Kugler Press, Netherlands, 1999, 169-174.
Salt, A.N. and DeMott, J.E. Physical Processes underlying homeostasis of cochlear endolymph. In: Intracranial and inner ear physiology and pathophysiology: Eds. Reid, A., , Marchbanks, R. and Ernst, A., Whurr publishers, London, 1998.
Salt, A.N.: Longitudinal fluid movements in the cochlea under normal and abnormal conditions. In: Intracranial and Intralabyrinthine fluids. Basic aspects and clinical applications Eds. Ernst, A., Marchbanks, R. and Samii, M., Springer Press, 1996, 23-30.
Salt, A.N. and DeMott, J.E.: Small longitudinal movements of endolymph are induced by volume disturbances. In: Meniere's Disease: 16th Danavox Symposium, Eds. Vesterhauge, S., Katholm, M. and Mikines, P. Danavox press, 1995, 113-122.
Thalmann, R., Salt, A.N. and DeMott, J.: Endolymph volume regulation: Possible mechanisms. In: Ménière's Disease. Ed., J.B. Nadol, Kugler, Amsterdam, pp. 55-60, 1989.
Salt, A.N. and Thalmann, R.: Rate of longitudinal flow of cochlear endolymph. In: Ménière's Disease. Ed., J.B. Nadol, Kugler, Amsterdam, pp. 69-73, 1989.
Salt, A.N. and Thalmann, R.: Cochlear fluid dynamics. In: Physiology of the Ear. Eds., A.F. Jahn and J.R. Santos-Sacchi, Raven Press, New York, pp. 341-357, 1988.
Salt, A.N. and Konishi, T.: The cochlear fluids: endolymph and perilymph. In: Neurobiology of Hearing: The Cochlea. Eds. R. Altschuler et al., Raven Press, N.Y., pp. 109-122, 1986.
Salt, A.N. and Thornton, A.R.D.: The choice of stimulus polarity for brainstem responses in the clinic. In: Evoked Potentials II. Eds. R.H. Nodar and C. Barbar, Butterworth Press, Boston, pp. 203-215, 1984.
Konishi, T., Salt, A.N. and Kimura, R.S.: Electrophysiological studies of experimentally-induced endolymphatic hydrops in guinea pigs. In: Meniere's disease-pathogenesis and treatment. Eds. K-H. Vosteen et al., Georg Thieme Verlag, N.Y. pp.47-58, 1981.
Abstracts / Presentations
Hahn, H., Salt, A. N., Zenner, H.-P., Plontke, S. The effect of microdialysis on substance concentrations in small fluid compartments. 40th Inner Ear Biology Meeting, Granada, Spain, September 2003.Plontke, S., Siedow, N., Wegener, R., Zenner, H-P., Salt, A.N. 3-D-and 1-D computer simulation of drug distribution in inner ear fluids after local application to the round window membrane Third International Symposium on Inner Ear Pharmacology, Málaga-Spain, September 5-6, 2003.
Lee, S.C., Bohne, B.A., Harding, G.W., Salt, A.N. Can infrasound protect the cochlea from a damaging level of noise? 26th Midwinter Research Meeting of the ARO, 2003.
Salt, A.N., Kellner, C., Hale, S. Quantification of cerbrospinal fluid contamination of perilymph samples taken from the basal cochlear turn. 26th Midwinter Research Meeting of the ARO, 2003.
Plontke, S.K.R., Salt, A.N. Simulation of corticosteroid pharmacokinetics in the inner ear fluids. 26th Midwinter Research Meeting of the ARO, 2003.
Sirjani, D.B., Hughes, R., Salt, A.N. Cochlear responses to acute endolymph volume changes. 26th Midwinter Research Meeting of the ARO, 2003.
Linder, B., Rask-Anderson, H., Salt, A. Migration of bone marrow cells into the endolymphatic sac induced by microinjection of artificial endolymph into the cochlea. 25th Midwinter Research Meeting of the ARO, 2002.
Plontke, S.K.R., Wood, A.W., Salt, A.N. Simulation of gentamicin distribution in inner ear fluids with round window application. 25th Midwinter Research Meeting of the ARO, 2002.
Salt, A.N., DeMott, J.E., Hale, S.A. Acute endolymphatic hydrops is induced by non-traumatizing low frequency stimulation. 25th Midwinter Research Meeting of the ARO, 2002.
Pettit, K., DeMott, J., Henson, M., Henson, O., Salt, A. Quantitative anatomy of the guinea pig endolymphatic sac determined from 3-D magnetic resonance and histologic images. 24th Midwinter Research Meeting of the ARO, 2001.
DeMott, J., Salt, A. Responses of the endolymphatic sac to perilymphatic pressure changes. 24th Midwinter Research Meeting of the ARO, 2001.
Salt, A.N., DeMott, J.E. Responses of the endolymphatic sac to volume changes. 37th Workshop on Inner Ear Biology, Uppsala, Sweden, p32, 2000.
Salt, A.N. Do clinical treatments for Meniere's disease reduce endolymphatic hydrops? Proceedings of the XXV International Congress of Audiology, The Hague, The Netherlands, p64, 2000
Rask-Anderson, H., Salt, A., DeMott, J. Ultrastructural changes of the endolymphatic sac following microinjection and withdrawal of endolymph. 23rd Midwinter Research Meeting of the ARO, 2000.
Salt, A., Ma, Y. Simulation of solute entry into cochlear fluids through the round window membrane. 23rd Midwinter Research Meeting of the ARO, 2000.
DeMott, J., Salt, A. Ionic changes in the endolymphatic sac during volume manipulations. 23rd Midwinter Research Meeting of the ARO, 2000.
Ghiz, A., Salt, A.N., DeMott, J., Henson, M., Henson, O.W. Quantification of inner ear structures from 3-D reconstructions of magnetic resonance images. 23rd Midwinter Research Meeting of the ARO, 2000.
Ma, Y., Salt, A.N. Effectiveness of manipulating cochlear perilymph by injections: A quantitative analysis. 23rd Midwinter Research Meeting of the ARO, 2000.
DeMott, J.E., Thorne, M., Salt, A.N., Henson, M.M., Henson, O.W., jr., Gewalt, S.L. Cochlear fluid space dimensions for six species derived from 3-D magnetic resonance images. 22nd Midwinter Research Meeting of the ARO, 1999.
Salt, A. N. A program for the simulation of solute movements in the cochlea. 22nd Midwinter Research Meeting of the ARO, 1999.
Salt, A.N. Techniques with respect to cochlear homeostasis (Workshop) 21st Midwinter Research Meeting of the ARO, 1998.
Rask-Andersen, H., Salt, A.N., DeMott, J.E., Hultcrantz, M. and Bagger_Sjoback, D. Morphologic changes of the endolymphatic sac induced by microinjection of artificial endolymph into the cochlea. 21st Midwinter Research Meeting of the ARO, 1998.
Ma, Y.L., Salt, A.N. and DeMott, J.E. Endolymphatic changes induced by cochlear perfusion with artificial perilymph. 21st Midwinter Research Meeting of the ARO, 1998.
DeMott, J.E. and Salt, A.N. Induction of longitudinal endolymph movements by perilymphatic injections. 21st Midwinter Research Meeting of the ARO, 1998.
Salt, A.N. and DeMott, J.E. Cochlear responses to infrasound in the 0.1 to 20 Hz range. 21st Midwinter Research Meeting of the ARO, 1998.
DeMott, J.E. and Salt, A.N. Undetectable pressure increase during induction of acute endolymphatic hydrops by microinjection. 20th Midwinter Research Meeting of the ARO, 1997. Abstract available
Brunschwig, A., Salt, A.N., DeMott, J.E., Henson, M.M. and Gewalt, S.L. Fixation- induced shrinkage of Reissner's membrane and its potential influence on the assessment of endolymph volume. 20th Midwinter Research Meeting of the ARO, 1997. Abstract available
Ma, Y., Salt, A.N. and Suzuki, M. Dependence of endolymph pH on perilymph bicarbonate concentration. 20th Midwinter Research Meeting of the ARO, 1997. Abstract available
Salt, A.N. and DeMott, J.E.: Evidence for two components of endolymph volume regulation involving local and flow-based mechanisms. 19th Midwinter Research Meeting of the ARO, 1996.
DeMott, J.E. and Salt, A.N.:Perilymph potassium increases during acute endolymph volume enlargement. 19th Midwinter Research Meeting of the ARO, 1996.
Suzuki, M. and Salt, A.N.: Endocochlear potential and cochlear fluid pH changes induced by respiratory CO2 manipulations. 19th Midwinter Research Meeting of the ARO, 1996.
Gill, S.S. and Salt, A.N.: Endolymph calcium homeostasis in pigmented and albino guinea pigs. 19th Midwinter Research Meeting of the ARO, 1996.
Salt, A.N. and DeMott, J.E.: Endolymph volume regulation mechanisms revealed by microinjections into scala media. Journal of the Acoustical Society of America 98, 2945, 1995.
DeMott, J.D. and Salt, A.N. : Longitudinal movements and area changes of endolymph produced by osmotic dehydration. 18th Midwinter Research Meeting of the ARO, 1995
Robey T.C., Miller, D.A., Salt, A.N. and Fredrickson, J.M.: The use of evoked potential recordings and stapes displacement measurements to evaluate the in vivo function of an implantable electromagnetic middle ear transducer. American Otological Society. 1995
Henson, M.M Henson, Keating, A.W. Keating, Henson, O.W. Henson, Gewalt, S.L. , Johnson, G.A., Salt, A.N. and DeMott, J.: A method for reconstruction and quantification of cochlear fluid-filled spaces. 18th Midwinter Research Meeting of the ARO, 1995
Miller, D.M. and Salt, A.N.: Endolymph composition measurements in the Wv mouse mutant. 18th Midwinter Research Meeting of the ARO, 1995
Gill, S. and Salt, A.N.: Endolymph calcium differences between pigmented and albino guinea pigs. 18th Midwinter Research Meeting of the ARO, 1995
Salt, A.N., Henson, M.M., DeMott, J.D., Henson, O.W.: Quantification of endolymphatic hydrops in the guinea-pig cochlea by Magnetic Resonance Microscopy. 18th Midwinter Research Meeting of the ARO, 1995
Salt, A.N., DeMott, J.D. and Kimura, R.: Comparison of in vivo and histologic methods of quantifying endolymphatic hydrops. 17th Midwinter Research Meeting of the ARO, 1994
Tanaka, M. and Salt, A.N.: Cochlear function is disturbed by small increases of endolymph Ca. 17th Midwinter Research Meeting of the ARO, 1994
Salt, A.N.: Inner ear fluid flow. 17th Midwinter Research meeting of the ARO, 1994 Presidential Symposium: Homeostatic Mechanisms of the Inner Ear.
DeMott, J. and Salt, A.N.: Time course of endolymphatic hydrops development in guinea-pigs measured with an ionic volume marker in vivo. 16th Midwinter meeting of the ARO 1993
Salt, A.N. and Vora, A.R.: Second harmonic distortion increases in hydropic and calcium-injected cochleas. 16th Midwinter meeting of the ARO 1993
Ito, Z. and Salt, A.N.: Comparison of solute movements across the blood-perilymph barrier in different regions of the cochlea. 15th Midwinter Research Meeting of the ARO 1992
Salt, A.N. and DeMott, J.: Endolymph calcium increases with time in hydropic guinea-pigs. 15th Midwinter Research Meeting of the ARO 1992
Ito, Z., Salt, A.N. and Thalmann, R.: Solute movements across the round window membrane. 14th Midwinter Res. Meet, ARO, 1991
Salt, A.N., DeMott, J. and Thalmann, R.: Measurement of endolymph volume in vivo in guinea pigs with endolymphatic hydrops. 14th Midwinter Res. Meet, ARO, 1991 (Abstract)
Salt, A.N. and Vora, A.R.: Thresholds to continuous tones measured using the cochlear action potential response. 27th Workshop on Inner Ear Biology, Sweden, June 1990.
Garcia, P and Salt, A.N.: Comparison of AP tuning curves generated by amplitude reduction and derived response techniques. 13th Midwinter Res. Meet, ARO, p.148, 1990
Salt, A.N., Inamura, N. and Thalmann, R. Evidence for a tight barrier between blood and cochlear perilymph. 13th Midwinter Res. Meet. ARO, p.381, 1990
Inamura, N., Salt, A.N. and Thalmann, R.: Evidence for a tight blood-labyrinth barrier. J. Acoust. Soc. Amer. 86:S96, 1989
Garcia, P. and Salt, A.N.: Action potential tuning curves recorded with a derived response technique. J. Acoust. Soc. Amer. 86:S96, 1989
Inamura, N., Salt, A.N., Thalmann, R. and Vora, A.: Volume flow of perilymph in the fistulized cochlea. 26th Workshop on Inner Ear Biology, France, Sept. 1989.
Inamura, N., Salt, A.N., Thalmann, R. and Vora, A.: Perilymph volume flow in the fistulized cochlea. J. Acoust. Soc. Amer. 85:S35-S36, 1989.
Salt, A.N., Thalmann, R. and DeMott, J.: A negative correlation between endocochlear potential and endolymph potassium concentration. J. Acoust. Soc. Amer. 85:S68-S69, 1989.
Thalmann, R., Salt, A.N. and DeMott, J.: Local regulation of endolymph volume in the cochlea. Proc. 12th Midwinter Res. Meet. Assoc. ARO, p. 106, 1989.
Inamura, N., Salt, A.N., Arakawa, E. and Thalmann, R.: Ionic gradients within the endolymphatic space of the guinea-pig. Proc. 12th Midwinter Res. Meet. Assoc. ARO, pp.128-129, 1989.
Salt, A.N., Ohyama, K. and Thalmann, R.: Homeostasis of potassium in cochlear perilymph. Proc. 12th Midwinter Res. Meet. Assoc. ARO, pp. 127-128, 1989.
Thalmann, R., Salt, A.N. and DeMott, J.: A local cochlear mechanism of endolymph volume regulation. J. Acoust. Soc. Amer. 84:S54, 1988.
Ohyama, K., Salt, A.N. and Thalmann, R.: Radial communication between the perilymphatic scalae of the cochlea. 11th Midwinter ARO, pp. 180-181, 1988.
Salt, A.N., DeMott, J. and Thalmann, R.: Dependence of endolymph potassium concentration on calcium. 11th Midwinter Meeting ARO, pp. 179-180, 1988.
Thalmann, R. and Salt, A.N.: Disorders of inner ear fluid regulation. Washington Univ. N.I.H. Centennial Celebration, Oct. 1987.
Hara, A., Salt, A.N., Varghese, J. and Thalmann, R.: Quantification of cerebrospinal fluid (CSF) contamination of scala tympani (ST) perilymph samples. J. Acoust. Soc. Amer. 82:S70, 1987.
Salt, A.N., Vora, A.R. and Thalmann, R.: Frequency specificity of the cochlear action potential varies with stimulus presentation rate. J. Acoust. Soc. Amer. 82:S59, 1987.
Ohyama, K., Salt, A.N. and Thalmann, R.: Perilymph volume flow measured under physiological conditons. J. Acoust. Soc. Amer. 81:S6-S7, 1987.
Salt, A.N., Melichar, I. and Thalmann, R.: Mechanism of endocochlear potential generation by stria vascularis. J. Acoust. Soc. Amer., 81:S7, 1987.
Hara, A., Thalmann, R. and Salt, A.N.: Pronounced differences in blood/perilymph kinetics of furosemide between scala vestibuli and scala tympani. Paradoxical effect of low level probenecid. Proc. 10th Midwinter Res. Meet. Assoc. ARO, 1987, pp.25-26.
Ohyama, K., Salt, A.N. and Thalmann, R.: Rate of perilymph flow in the guinea pig cochlea. Proc. 10th Midwinter Res. Meet. Assoc. ARO, 1987, p.26.
Salt, A.N. and Thalmann, R.: A physiologic technique for the measurement of endolymph flow rate and cross-sectional area in the guinea pig cochlea in vivo. Proc. 10th Midwinter Res. Meet. Assoc. ARO, 1987, p.27.
Hara, A., Thalmann, R. and Salt, A.N.: Marked differences in blood/perilymph kinetics of furosemide (FU) between scala tympani (ST)and scala vestibuli (SV). Paradoxical effect of probenecid (PR). Acoust. Soc. Amer. 80:S76, 1986.
Ohyama, K., Arakawa, E., Salt, A.N. and Thalmann, R.: Static and dynamic differences in perilymphatic potassium between scala tympani (ST) and scala vestibuli (SV). J. Acoust. Soc. Amer. 80:S76, 1986
Salt, A.N., Thalmann, R., Marcus, D.C. and Bohne, B.A.: Direct measurement of longitudinal movement of tracer in cochlear endolymph. J. Acoust. Soc. Amer., 78:S66, 1985.
Salt, A.N., Thalmann, R., Marcus, D.C. and Bohne, B.A.: Rate of longitudinal endolymph flow in the mammalian cochlea measured by a direct, ion-selective microelectrode technique. 22nd Workshop on Inner Ear Biology, Wurzburg, West Germany, p.75, 1985. (Abstract).
Salt, A.N. and Thornton, A.R.D.: Possible mechanisms for the changes of auditory responses due to stimulus polarity. Brit. J. Audiol. 17:117, 1983.
Konishi, T. and Salt, A.N.: Electrochemical profile for potassium ions across the hair cell membranes. Proc. of the International Symposium on Hearing, Germany 1983.
Salt, A.N. and Thornton, A.R.D.: Effects of stimulus polarity on the auditory brainstem responses studied with slow rise-time stimuli. Proc. First ABR Standards Symposium, University of California, 1982.
Parker, D.J. and Salt, A.N.: Factors affecting the binaural interaction of the auditory brainstem response. Brit. J. Audiol. 16:69-70, 1982.
Konishi, T. and Salt, A.N.: Electrochemical profile for K across the hair cell membrane of the organ of Corti. Proc. 4th Midwinter Res. Meet. Assoc. ARO, pp.56-57, 1981.
Konishi, T., Salt, A.N. and Hamrick, P.E.: Effects of hypothermia on ionic movement in the guinea pig. J. Acoust. Soc. Amer. 68:S43, 1980.
Cook, R.O., Konishi, T., Salt, A.N. and Hamm, C.V.: Hearing levels of guinea pigs exposed to elevated noise levels in utero. J. Acoust. Soc. Amer. 68:S98, 1980.
Konishi, T. and Salt, A.N.: Permeability to potassium of the endolymph-perilymph barrier and its possible relation to cochlear transduction. Proc. 3rd Midwinter Res. Assoc. ARO, 1980.
Salt, A.N. and Konishi, T.: Further observations on the nature of negative endocochlear potential. Proc. 3rd Midwinter Res. Meet. Assoc. ARO, 1980.
Salt, A.N. and Konishi, T.: The role of potassium and sodium in cochlear transduction- a study with amiloride and tetraethylammonium. J. Acoust. Soc. Amer. 66:S47, 1979.
Konishi, T., Salt, A.N. and Hamrick, P.E.: Effects of exposure to noise on electrolyte transport in the guinea pig cochlea. J. Acoust. Soc. Amer. 64:S132, 1978.
Salt, A.N. and Stopp, P.E.: Behaviour of tone-induced cochlear responses to potassium concentration elevated by scala tympani perfusion and monitored by ion- selective microelectrodes. J. Acoust. Soc. Amer. 64:S132, 1978.
Konishi, T., Salt, A.N. and Hamrick, P.E.: Effects of exposure to noise on cochlear potentials and potassium ion activity in guinea pigs. J. Acoust. Soc. Amer. 64:S132, 1978.
Salt, A.N., Konishi, T., Akay, A. and Cook, R.O.: Comparison of impact noise and continuous noise on cochlear function. J.Acoust. Soc. Amer. 64:S132, 1978.
Comis, S.D., Salt, A.N. and Stopp, P.E.: A perfusion technique for the study of cochlear function. J. Physiol. 256:63, 1976.
