Studies of the Relationship between the Round Window and Scala Tympani
Project completed by Adam F. Ghiz, B.S., Summer 1999
Recent advances in magnetic resonance (MR) imaging have allowed visualization of the 3-D structure of the round window at the base of scala tympani.
This figure shows slices through different regions of the round window. The specimen has been oriented so that the round window is orthogonal to the plane of slicing. The round window surface in each slice was tagged yellow, as shown in the lower panels. The surface area of round window was then quantified for each specimen.
Scala tympani was tagged red, as shown above. Using a cross-sectional area algorithm, the base of scala tympani was approximated as a straight tube. A white line was drawn down the middle of the tube. The specimen was rotated and resliced vertically, with the plane of section across the scala, as shown by the blue lines in panel C.
Selected representative sections of the vertical reslice are shown above for one guinea pig cochlea. Each section shows an area of scala tympani in contact with a corresponding area of the round window membrane. The numeric data derived from this analysis are used in models simulating the cochlear fluids. These data are to be published in the near future and will be summarized on this page after publication.
Movies Showing 3-D Structures
The 3-D geometry of the relationship between the round window, the scala tympani, and their surrounding structures is often not appreciated from conventional histological sections. The following movies illustrate these structural relationships.
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Round Window relationship to Scala Tympani
All Structures
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  View 1.0 MB Quicktime Movie
Round Window and Scala Tympani only
  View 49 KB Quicktime Movie
Round Window only
  View 100 KB Quicktime Movie
Note that the round window membrane is not exacly round in shape, rather it is shaped more like a popular American potato chip - The Pringle.