Selected Publications for the Work Carried out
by the Team at Washington University
All other references can
be found under a specific protein and in Method (when available MEDLINE link
is provided):
A review
article has recently been published: Thalmann I: Proteomics and the
inner ear. Disease Markers. 17:259-270, 2001
Preparatory methods for tissues and fluids
Thalmann R (1976) Quantitative histo-and
cytochemistry of the ear. In "The Handbook of Auditory and Vestibular Research
Methods. CA Smith and J A Vernon (Eds.); CC Thomas, Springfield, IL, Part
Biochemistry, pp. 359-419.
MEDLINE
5081743 Thalmann R, Thalmann I, Comegys
TH (1972) Quantitative cytochemistry of the organ of Corti. Dissection,
weight determination and analysis of single outer hair cells. Laryngoscope
82:2059-2078.
MEDLINE
4320416 Thalmann R, Thalmann I, Comegys TH (1970) Dissection
and chemical analysis of substructures of the organ of Corti. Laryngoscope
80:1619-1645.
OCP1 and OCP2
MEDLINE911470190
Henzl MT, O'Neal J, Killick
R, Thalmann I, Thalmann R (2001) OCP1, an F-box protein, co-localizes with
OCP2/SKP1 in the cochlear epithelial gap junction region. Hear Res157:100-111,
2001.
MEDLINE
9872132 Henzl, MT, Thalmann I, Thalmann R (1998) OCP2 exists
as a dimer in the organ of Corti. Hearing Res 126:37-46.
MEDLINE
9105463 Thalmann R, Henzl MT, Thalmann I (1997) Specific proteins of
the organ of Corti. Acta Otolaryngol. 117:265-268.
MEDLINE
9119766 Yoho ER, Thomopoulos GN, Thalmann I., Thalmann R, Schulte
BA (1997) Localization of organ of Corti protein II in the adult and developing
gerbil cochlea. Hearing Res 104:47-56.
MEDLINE
7558018 Chen H, Thalmann I, Adams JC, Avraham KB, Copeland NG,
Jenkins NS, Beier DR, Corey DP, Thalmann R, Duyk GM (1995) cDNA cloning,
tissue distribution, and chromosomal localization of Ocp2, a gene
encoding a putative transcription-associated factor predominantly expressed
in the auditory organs. Genomics 27:389-398.
MEDLINE
8432690 Thalmann I, Suzuki H, McCourt DW, Comegys TH, Thalmann
R (1993): Partial amino acid sequence of organ of Corti proteins OCP1 and
OCP2: A progress report. Hearing Res 64:191-198.
Thalmann I, Rosenthal HL, Moore BW, Thalmann
R (1980) Organ of Corti specific polypeptides: OCP-I and OCP-II. Arch Otorhinolaryngol
226:123-128.
Oncomodulin
Thalmann I, Thalmann R, Henzl MT (1998) Novel
calcium sensor in the outer hair cells: Quantitation of oncomodulin. Prim
Sensory Neuron, Highlights in Hair Cell Biology, 2:283-296.
MEDLINE
9405492 Sakaguchi N, Henzl M, Thalmann I, Thalmann R, Schulte BA (1998)
Oncomodulin is expressed exclusively by outer hair cells in the organ of
Corti. J Histochem Cytochem 46:29-39.
MEDLINE
9112110 Henzl MT, Shibasaki O, Comegys TH, Thalmann I, Thalmann
R (1997) Oncomodulin is a major protein in the organ of Corti. Hearing
Res 106:105-111.
MEDLINE
8974994 Senarita M, Thalmann I., Shibasaki O, Thalmann R. (1995)
Calcium-binding proteins in organ of Corti and basilar papilla: CBP-15,
an unidentified calcium-binding protein of the inner ear. Hearing Res 90:169-175.
MEDLINE
7575581 Thalmann I, Shibasaki O, Comegys TH, Henzl MT, Senarita
M, Thalmann R (1995) Detection of a beta-parvalbumin isoform in the mammalian
inner ear. Biochem Biophys Res Comm 215:142-147.
Protein profile of inner ear fluids and potential
application to diagnosis of perilymph fistula
MEDLINE
10380730 Thalmann R, Thalmann I (1999) Source and role of endolymph
macromolecules. Acta Otolaryngol 119:293-6.
MEDLINE
9105463 Thalmann R, Henzl MT, Thalmann I (1997) Specific proteins
of the organ of Corti. Acta Otolaryngol 117:265-8.
MEDLINE
8572113 Thalmann I, Kohut RI, Ryu JH, Thalmann R (1995) High resolution
two-dimensional electrophoresis: Technique and potential applicability
to the study of inner ear disease. Amer J Otol 16:153-157.
Thalmann I, Neely JG (1995) Progressive hearing
loss and the perilymphatic fistula. Seminars in Hearing 16:214-219.
MEDLINE
8084635 Thalmann I, Kohut RI Ryu JH, Senarita M, Thalmann R (1994)
Protein profile of human perilymph. In search of a marker for the diagnosis
of perilymph fistula. Otolaryngology - Head & Neck Surg 111:273-80.
MEDLINE
1464573Thalmann I, Ito Z, Thalmann R. (1992) Protein profiles of perilymph
and endolymph of the guinea pig. Hearing Res 63:37-42.
Otoconin-90
MEDLINE
10366455
Thalmann R, Ignatova E, Kachar B, Ornitz DM, Thalmann I (2001) Development
and maintenance of otoconia: biochemical considerations. Ann NY Acad Sci
942:162-78.
MEDLINE
10366455 Hurle B, Lane K, Kenney J, Tarantino LM, Bucan
M, Brownstein BH, Ornitz DM (2001) Physical mapping of the mouse tilted
locus identifies an association between human deafness loci DFNA6/14 and
vestibular system development. Genomics 77:189-199.
MEDLINE
10366455 Lins U, Farina M, Kurc M, Riordan G, Thalmann
R, Thalmann I, Kachar B (2000) The otoconia of the guinea pig utricle:
internal structure, surface exposure and interactions with the filament
matrix. J Struct Biol, 131:67-78.
MEDLINE
10366455 Thalmann R, Thalmann I (1999) Source and role
of endolymph macromolecules. Acta Otolaryngol 119:293-6.
MEDLINE
10366455 Wang Y, Thalmann I, Thalmann R, Ornitz DM (1999) Mapping
the mouse otoconin-90 (Oc90) gene to chromosome 15. Genomics 58:214-5.
MEDLINE
10380730 Thalmann R, Thalmann I (1999) Source and role of endolymph
macromolecules. Acta Otolaryngol 119:293-6.
MEDLINE
9860971 Wang Y, Kowalski PE, Thalmann I, Ornitz DM, Mager DL,
Thalmann R (1998) Otoconin-90, the mammalian otoconial matrix protein,
contains two domains of homology to secretory phospholipase A2. Proc Natl
Acad Sci USA 95:15345-50.
MEDLINE
9714575 Ornitz DM, Bohne BA, Thalmann I, Harding GW, Thalmann
R (1998) Otoconial agenesis in tilted mutant mice. Hearing Res 122:60-70.