Department of Otolaryngology

Sensory Regeneration Lab

Fay and Carl Simons Center for the Biology of Hearing & Deafness

Sensory transduction in the inner ear is mediated by mechanoreceptive hair cells. Unfortunately, hair cells can be injured or lost after exposure to noise, ototoxic drugs, or as part of normal aging. Such injury typically results in permanent hearing loss and/or disequilibrium. Our research focuses on the biological mechanisms that regulate the production of hair cells and the survival and growth of their afferent neurons.