Matthew A. Shew, MD

Assistant Professor
Otolaryngology—Head & Neck Surgery

Patients seen at

Ear, Nose and Throat Center
Center for Advanced Medicine
4921 Parkview Pl., Ste. A, Floor 11
St. Louis, MO 63110
(314) 362-7509
Fax: (314) 747-5592

WU Center for Hearing & Balance Disorders
226 S Woods Mill Road
Suite 58 West
Chesterfield, MO 63017
Phone: 314-453-0001
Fax: 314-453-0489

Mailing address

Washington University School  of Medicine
Dept. Otolaryngology-Head & Neck Surgery
660 S. Euclid Ave.
Campus Box 8115
St. Louis, MO  63110

Clinical interests

Dr. Shew’s clinical interests include otology, neurotology and skull base surgery.


  • Undergraduate: Biochemistry, Bowdoin College (2009)
  • MD: University of Indiana School of Medicine (2014)
  • Residency: University of Kansas (2019)
  • Fellowship: Neurotology, Washington University in St. Louis (2021)

Licensure and board certification

  • Otolaryngology–Certified


  • Centralized Otolaryngology Research Efforts (CORE) – AAO-HNSF Resident Research Award. 2018 – 2019. $10,000. Shew M, Wichova H, Sykes K, Staecker H.  Meniere’s: Evaluation of microRNA profiles of human inner ear perilymph.
  • American Neurotology Society Trainee Award, 2019
  • Department of Otolaryngology Basic Science Award,  2016-2019
  • Oscar T Pinsker Otologist Resident Award, 2017-2018
  • Devaiah Award for Excellence in Scientific Contributions, 2017-18, 2018-19
  • Midwest Head & Neck Consortium 1st Place – Best Presentation, 2018
  • Book Award for Excellence on ABOto In-Service Examination, 2015
  • Edward C. Weisberger MD Award – Most Outstanding Senior Medical Student in Otolaryngology, 2014
  • IU Melvin and Bren Simon Cancer Center William J. Wright Scholarship, 2013
  • Medical Student Council and Deans for Medical Student Research Committee, 2010-2013
  • Student Research Program in Academic Medicine Fellowship, 2011

Selected publications

  1. Hiatt K, Lewis D, Shew M, Bijangi-Vishehsaraei K, S Halum. Ciliary neurotrophic factor (CNTF) promotes skeletal muscle progenitor cell (MPC) viability via the phoshatidylinositol 3-kinase-Akt pathway. Journal of Tissue Engineer and Regenerative Medicine. 2012 Nov; 8(12) 963-968. PMID 23147834  
  2. McRae BR, Shew M, Aaron GP, Bijangi-Visheshsaraei K, SL Halum. A rapid novel model of culturing cranial nerve X-derived motorneurons for screening trophic factors outgrowth response.  Neurological Research. 2012 Jul: 34(6) 564-75. PMID 22663932
  3. Staser K, Shew MA, Michels EG, Mwanthi MM, Yang FC, Clapp DW, SJ Park. A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.  Experimental Hematology. 2013 Jan; 41(1) 56-66. PMID 23063725.  
  4. Staser K, Park SJ, Rhodes SD, Zeng Y, He YZ, Shew MA, Gehlhausen JR, Cerabona D, Menon K, Chen S, Sun Z, Yuan J, Ingram DA, Nalepa G, Yang FC, Clapp DW. Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk. Journal of Clinical Investigation. 2013 Jan; 123(1) 329-334. PMID 23221339  
  5. Gehlhausen JR, Park SJ, Shew MA, Staser K, Rhodes SD, Menon K, Lajiness J, Mwanthi M, Wang X, Yuan J, Samuels B, Territo P, Nalepa G, Yang FC, Conway S, Giovannini M, Stemmer-Rachamimov AS, Yates CW, and DW Clapp. A Murine Model of Neurofibromatosis Type 2 that accurately phenocopies human schwannoma formation. Human Molecular Genetics. 2015 Jan; 24(1) 1-8. PMID 25113746.  
  6. Shew MA, Jiang Z, Bruegger D, and Arganbright J. Migrated Esophageal Foreign Body presents as acute onset dysphagia years later: a case report.  International Journal of Pediatric Otorhinolaryngology. 2015 Dec; 79(12) 2460-2462.  PMID 26541295  
  7. Shew M, Twafik O, Lin J. Langerhans’s Cell Histiocytosis in an immunosuppressed patient isolated to the temporal bone.  Otology & Neurotology. 2016 Jul; 37(6) e194-196. PMID 27093030  
  8. Shew MA, Carlisle MP, Humphrey C, Kriet JD. Surgical treatment of orbital blowout fractures: complications and postoperative care patterns. Craniomaxillofacial Trauma and Reconstruction. 2016 Nov; 9(4) 299-304. PMID 27833708  
  9. Shew M, Bertsch J, Cammarata P, Staecker H. MRI imaging in an NF2 patient with a novel MRI compatible auditory brain stem implant.  Journal of Neurological Surgery Reports. 2017 Jan; 78(1) e12-e14. PMID 28210535  
  10. Muelleman T, Shew M, Subbarayan R, Shum A, Sykes K, Staecker H, Lin J. Epidemiology of dizzy patient population in a neurotology clinic and predictors of peripheral etiology. Otology & Neurotology. 2017 Jul; 38(6) 870-875. PMID 28498271  
  11. Shew M, Bush J, Tawfik O, Ator G. Middle ear polyp mimicking glomus tympanicum in a male adolescent. Otology & Neurotology. 2017 Aug; 38(7) e211-213. PMID 2859100  
  12. Shew M, Kriet JD, Humphrey CD. Flap Basics II: Advancement Flaps. Facial Plastic Surgery Clinics of North America. 2017 Aug; 25(3) 323-335. PMID 28676160  
  13. Muelleman T, Shew M, Alvi S, Shah K, Chamoun R, Staecker H, Lin J. Endoscopically assisted drilling, exposure of the fundus through a presigmoid retrolabyrinthine approach—a cadaveric feasibility study. Otolaryngology- Head and Neck Surgery. 2018 Jan; 155-157. PMID 28948858  
  14. Muelleman T, Shew M, Muelleman R, Villwock M, Sykes K, Staecker H, Lin J. The impact of resident participation on operative time and outcomes in otologic surgery. Otolaryngology-Head and Neck Surgery. 2018 Jan; 158(1) 155-157. PMID 29039248  
  15. Shew M, Muelleman T, Muelleman R, Villwock M, Sykes K, Staecker H, Lin J. Therapeutic mastoidectomy does not increase post-operative complications in the management of the chronic ear. Otology & Neurotology. 2018 Jan; 39(1) 54-58. PMID 29076928  
  16. Muelleman T, Shew M, Villwock M, Muelleman B, Sykes K, Staecker H, Lin J. Obesity does not increase operative time in otologic surgery: an analysis of 5125 cases. Otology & Neurotology. 2018 Feb; 39(2) e103-107. PMID 29315184  
  17. Shew M, Kavookjian H, Dahlstrom K, Muelleman T, Lin J, Camarata P, Ledbetter L, and Hinrich Staecker. Incidence and risk factors for sigmoid venous thrombosis following CPA tumor resection. Otology & Neurotology. 2018 Jun;38(5): e376-380. PMID 29738390  
  18. Shew M, Warnecke A, Lenarz T, Gunewardena S, and Staecker H. Feasibility of microRNA profiling in human inner ear perilymph. 2018 May; PMID 29781875  
  19. Shew M, Muelleman T, Harris M, Li M, Sykes K, Staecker H, Adunka O, Lin J. Petrous apex pneumatization: risk factor for CPA tumor postoperative CSF fistula. Annals of Otology, Rhinology & Laryngology. 2018 Jun; PMID 29925246  
  20. Wichova H, Alvi SA, Shew M, Lin J, Sale K, Larsen C, Staecker H. Tinnitus Perception in patients after vagal nerve stimulator implantation for epilepsy. American Journal of Otolaryngology. 2018 Sep-Oct;39(5): 599-602. PMID 30025741  
  21. Shew M, Wichova H, Lin J, Ledbetter L, Staecker H. Magnetic Resonance Imaging with Cochlear Implants and Auditory Brainstem Implants: Are We Truly Practicing MRI Safety?  Laryngoscope. 2018 Nov; PMID 30412276  
  22. Alvi S, Shew M, Wichova H, Lin J. Juxtafacial Lipoma of the Temporal Bone.  Otolaryngology-Head and Neck Surgery. 2018 Oct; PMID 30300565  
  23. Shew M, Shew ML, Bur AM. Otolaryngologists and Their Role in Vaccination For Prevention of HPV associated Head & Neck Cancer. Human Vaccines & Immunotherapeutics.  2018 Sept; PMID 30252604  
  24. Wichova H, Shew M, Alvi S, Lin J. A Case of Mesial Temporal Lobe Sclerosis Following Temporal Bone Encephalocele Repair for Medically Refractory Seizures. 2018 Nov 22;10(11):e3623; PMID 30693169  
  25. Shew M, New J, and Bur A. Using Machine Learning to Predict Delays in Adjuvant Radiation Following Surgery for Head and Neck Cancer. Otolaryngology Head & Neck Surgery. 2019 Jan; PMID 30691352  
  26. Bur A, Shew M, New J. Artificial Intelligence for the Otolaryngologist: A State of the Art Review.  Otolaryngology Head & Neck Surgery. 2019 Feb 5; PMID 30717624  
  27. Shew M, New J, Wichova H, Koestler D, and Staecker H. Using Machine Learning to Predict Sensorineural Hearing Loss Based on Perilymph Micro RNA Expression Profile.  Scientific Reports. 2019 March 4;9(1):3393; PMID 30833669  
  28. Bur AM, Holcomb A, Goodwin S, Woodroof J, Karadaghy O, Shnayder Y, Kakarala K, Brant J, Shew M. Machine Learning to Predict Occult Nodal Metastasis in Early Oral Squamaous cell carcinoma. Oral Oncology. 2019 May;92:20-25;  PMID 31010618  
  29. Karadaghy OA, Shew M, New J, Bur AM. Development and Assessment Machine Learning Model to Help Predict Survival Among Patients with Oral Squamous Cell Carcinoma. JAMA Otolaryngology Head & Neck Surgery. 2019 May 2. PMID 31045212  
  30. Boyd C, Shew M, Lin J. Temporal Bone Histopathology Case of the Month – Basal Cell Carcinoma of the Middle Ear Following Chemoradiation to the Head and Neck. Otology & Neurotology. 2019 May 30. PMID 31157722  
  31. Wichova H, Shew M, Staecker H. Utility of Perilymph MicroRNA Sampling for Identification of Active Gene Expression in pathways in Otosclerosis. Otology & Neurotology. 2019 Jul; 40(6):710-719. PMID 31192899  
  32. Muelleman T, Pippin K, Shew M, Villwock M, Quesnel A, Mckenna MD, Ledbetter L, and Staecker H. The size of internal auditory canal diverticula is unrelated to degree of hearing loss. Laryngoscope. 2019 Jun 24. PMID 3123321